Registration

Welcome and Opening

Session Chair:

KL01 - The Emergence of Antibody-Drug Conjugates (ADCs) as Targeted Cancer Therapies: From Ehrlich's "Magic Bullet" Concept to Calicheamicin γ1I and Mylotarg

OC01 - Functionalization of Tumour-Targeting Antibodies Via Enzymatic Oxidation of Tyrosine to 1,2-Quinones
Winner of the Young Medicinal Chemist Meeting in The Netherlands

OC02 - Synthetic Small Molecules Interfering with Oncogenic Micrornas for the Induction of Glioblastoma Stem Cells Differentiation
Winner of the Young Medicinal Chemist Meeting in France

OC03 -New Ruthenium-Cyclopentadienyl Complexes Bearing Biotinylated (Macro)Ligands: Targeting Strategies to Fight Metastatic Breast Cancer
Winner of the Young Medicinal Chemist Meeting in Portugal

Flash Poster Presentations (01-10)

FP01 - A New Life for Diazaborines: the Next Generation of Serine Protease Inhibitors

FP02 - From Peptides to Peptidomimetics: Structure-Activity Relationship of a Factor H-Binding Peptide to Modulate Undesired Host Complement Activity

FP03 - Matrix Metalloproteinase-12 Inhibitors: Synthesis, Structure-Activity Relationships and Intestinal Absorption of Novel Sugar-Based Biphenylsulfonamide Carboxylates

FP04 - Photophysical Properties and Antiparasitic Activity of Bodipy-Tethered Dinuclear Trithiolato-Bridged Ruthenium(II)-Arene Complexes

FP05 - N-ALKYL L-Iminosugars as Novel Anti-Inflammatory and Anti-Biofilm Tools for Cystic Fibrosis Lung Infections

FP06 - Design, Synthesis and Biological Evaluation of Novel Substituted Purine Isosters as EGFR Kinase Inhibitors, with Promising Pharmacokinetic Profile and In Vivo Efficacy

FP07 - Metal-Chelating Acetohydroxamic Acids Against Hepatitis C Virus and Flaviviruses

FP08 - Discovery of Small-Molecule Modulators of 14-3-3 PPIs Via Dynamic Combinatorial Chemistry

FP09 - Purine Nucleoside Analogs as Highly Potent Leads for the Treatment of Human African Trypanosomiasis

FP10 - Development of Allosteric Inhibitors of ColH Using DCC Strategy

Coffee Break

Session Chair:

OC04 - Novel Acridine Derivatives as TDP 1 and/or 2 Inhibitors
Winner of the Young Medicinal Chemist Meeting in Greece

OC05 - Discovery of a Novel Chemotype of Non-Acidic, Neutral and Macrocyclic Keap1 Inhibitors
Winner of the Young Medicinal Chemist Meeting in Sweden

OC06 - Directed Evolution of Short Peptides for Selective Detoxification of Lead
Winner of the Young Medicinal Chemist Meeting in Switzerland

Flash Poster Presentations (11-20)

FP11 - Identification, Synthesis and Optimization of Inhibitors of the Protein Tyrosine Phosphatase SHP2

FP12 - Multitarget Triazoles: an Innovative Approach for the Treatment of Alzheimer’s Disease

FP13 - TDP-43 Modulation by CDC7 Inhibitors as a Therapeutic Strategy for Amyotrophic Lateral Sclerosis

FP14 - Use of the 4-Hydroxy-Triazole Moiety as a Bioisosteric Tool in the Development of Selective Ligands for Subtypes Ampa Receptor

FP15 - In Vitro and In Ovo Evaluation of Ros-Activatable Anticancer Boronate Prodrugs of Doxorubicin

FP16 - Design and Synthesis of Tead's Ligands for the Treatment of Cancers

FP17 - Drug-Fragment Based Explorations for Novel Enterovirus Inhibitors

FP18 - Gemcitabine-GnRH Bioconjugates Bearing Oxime Bond Linkages: Synthesis, In Vitro Stability, Drug Release and Cytotoxic Effect

FP19 - Development of GSTO1-1 Inhibitors for the Treatment of Inflammatory Conditions

FP20 - Identification of a Novel Quinoline-Based DNA Demethylating Compound Highly Potent in Cancer Cells

EFMC-YMCS Poster Presentation Session 1 (Odd), Bites & Drinks

EFMC-YMCS Poster Presentation Session 2 (Even), Bites & Drinks

End of the Scientifc Programme

How to Boost Your Oral Presentation Skill, and Create a Good Slideshow

Getting the Job You Deserve!

EFMC-YSN Networking Event

End of the Day

Session Chair:

KL02 - Medicinal Chemistry Between Serendipity and (Artificial) Intelligence

OC07 - Antiplasmodial Activity of SAHAquines, Novel SAHA - Primaquine Hybrids
Winner of the Young Medicinal Chemist Meeting in Croatia

OC08 - Hybrdization Approach Towards Novel Antituberculars: Design, Synthesis, And Antimicrobial Evaluation Hybrid Compounds Combining Pyrazinamide and p Aminosalicylic Acid
Winner of the Young Medicinal Chemist Meeting in Czech Republic

OC09 - Synthesis, Computational and Biological Evaluation of Novel Benzimidazole Compounds for the Treatment of Cryptococcus Neoformans
Winner of the Young Medicinal Chemist Meeting in the United Kingdom

OC10 - Nʼ-Benzylated Derivatives of N-(7-Chloroquinolin-4-Yl)Octane-1,8-Diamine as Quorum Sensing Inhibitors in Pseudomonas Aeruginosa
Winner of the Young Medicinal Chemist Meeting in Serbia

Coffee Break

Session Chair:

OC11 - Geometric Isomers of N-Propargyl-4-Syrylpiperidine Discriminate Between Monoamine Oxidase Isoforms A and B
Winner of the Young Medicinal Chemist Meeting in Slovenia

OC12 A Fusing Strategy Application: Towards Potent ChE Inhibitors With MTDL Profile
Winner of the Young Medicinal Chemist Meeting in Turkey

OC13 - Development of Unique Molecular Probes: Low-Basicity Agonists for the Study of 5-HT7 Receptor Function
Winner of the Young Medicinal Chemist Meeting in Poland

OC14 - The Establishment of Tocopherol Reference Intervals for Hungarian Adult Population Using Validated HPLC Method
Winner of the Young Medicinal Chemist Meeting in Hungary

Lunch

Why Was My Paper Rejected? Tips from an Editor on How to Get Published

Session Chair:

OC15 - Expanding the Chemical Space of DNA-Encoded Small Molecule Libraries
Winner of the Young Medicinal Chemist Meeting in Germany

OC16 - Finding the Right Candidate for the Right Position: a Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders
Winner of the Young Medicinal Chemist Meeting in Spain

OC17 - From ZINC to ZINClick: Our Way to Explore the Chemical Space
Winner of the Young Medicinal Chemist Meeting in Italy

OC18 - Extended Glucuronides: Achieving Site-Selectivity Through Extracellular Drug Release
Winner of the Young Medicinal Chemist Meeting in Denmark

OC19 - Cyclopropenium-Based Polymers
Winner of the Young Medicinal Chemist Meeting in Israel

Voting Break

KL03 - Chemical Tools to Target and Image Tumours

Closing and Award Ceremony

End of the Symposium